Host Defense Lion’s Mane

Our Rating


  • Strong, trusted supplement brand
  • Good dosage (1000 mg of lion's mane (hericium erinaceus) per serving.
  • Clean ingredient profile that uses plant based capsules
Table of Contents

The Details

Host Defense Lion’s Mane passed all quality reviews and recorded 1000 mg of lion’s mane (hericium erinaceus) per serving.

In this review, we’ll get into the specifics of the most popular Host Defense lion’s mane mushroom supplement.

Host Defense is an industry veteran that is known for producing high-quality mushroom products. The company is one of the few online brands that actually uses organic lion’s mane mushroom in their formula.

In this Host Defense Lion’s Mane review, we take a quick look at their flagship ingredient formula, quality, and overall effectiveness.

Ingredients Rating

Ingredients rating

This product passed our ingredient review and met our active ingredient standards for overall effectiveness and safety. No flagged watch list ingredients were found during our review. No flagged inactive ingredients were recorded in this product.

Vegetarian capsules

Certified Organic

Non-GMO Project Verified

Heat treated to proper temperature for improved bioavailability

Other Ingredients: Freeze-dried myceliated brown rice ‡, pullulan (an extra-cellular polysaccharide).

Effectiveness Rating

Effectiveness rating

This supplement features Lion’s Mane (Hericium erinaceus) mycelium as its active ingredient, which is ideal for potential benefits such as cognitive and immunomodulator effects
Each serving contains 1000 mg of lion’s mane (hericium erinaceus) per serving. The exact dosage for optimal effects are still unknown.

Quality Rating

Quality rating

Host Defense Lion’s Mane is really a rather simple product. Organic lion’s mane mushroom that’s worked and made into capsules. Capsules are vegetarian friendly and no random ingredients were found in its formula.

Our opinion is that you can absolutely feel the quality of this lion’s mane product vs other brands on the market. If you’re in search of a clean supplement that uses organic ingredients and is made with a lot of care, you have to try this brand of lion’s mane.

Host Defense is one of the top brands in the industry when it comes to mushroom supplements. No flagged inactive ingredients were found during our review


Current research on the overall side effects of lion's mane is very limited. That being said, customers who report some mild side effects such as a mild skin rash or upset stomach. This can sometimes be due to an allergic reaction.

Yes. This supplement contains no animal products. The capsules are plant based too.

Follow instructions on the supplement label for best results. Test your reaction to this type of supplement with lower doses first if its your first time taking mushroom products.

Lion's mane supplementation has some clinical evidence showing its safe use when used appropriately; however, the evidence is limited by quantity, quality, or contradictory findings.

Lion's mane products like this one are "possibly safe" and appear to safe, but doesn't have quite enough high-quality evidence for all side effects to be known.

A majority of side effects that were noted by customers are are mild and may include stomach discomfort. There have been reports of allergic reactions.

It's always best to follow the supplement directions found on your Host Defense Lion’s Mane. The appropriate dose of lion's mane mushroom depends on several factors including your age, health, and several other conditions. At this time there isn't enough scientific information to determine which dosage would be best for lion's mane. Always consult your physician or healthcare professional before using.

We bought Host Defense Lion’s Mane so that we could review it. As always, however, we did not accept any money to write good or bad things about it. We review products independently.

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